I have. Parts of it are brilliant, parts of it are incredibly pretentious. Took me about a year to get through it.
DFW Is great. I'd recommend his essays to begin with ... Starting with This is Water, and the collection of essays - A supposedly fun thing I'd never do again and Consider the Lobster.
Brett,
Do you actually read any of the books you constantly ask opinions about? Or just compile a big lost of stuff to read and never work through it...(p.s I'm more of the latter myself )